Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR77WD repeat domain 77. (334 aa)    
Predicted Functional Partners:
clns1a
Chloride channel, nucleotide-sensitive, 1A.
   
 0.999
prmt5
Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.
   
 0.999
riok1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
 
 0.987
snrpd3
Small nuclear ribonucleoprotein Sm D3.
    
 0.986
ENSPFOP00000011845
Small nuclear ribonucleoprotein-associated protein.
   
 0.975
lsm4
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 
 0.964
LOC103137772
FIP1 like 1b (S. cerevisiae).
   
 0.964
cpsf1
Cleavage and polyadenylation specific factor 1.
   
 0.960
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.959
sympk
Symplekin.
    
 0.958
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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