Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
ENSPFOP00000001546Glypican 5b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (512 aa)    
Predicted Functional Partners:
ENSPFOP00000025518
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 0.866
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.726
dhh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.722
LOC103156544
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.722
LOC103140457
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.722
ihh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.722
LOC103156544-2
Indian hedgehog B protein-like.
    
 0.722
LOC103139868
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.695
gpc2
Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.695
ENSPFOP00000005909
Glypican 6b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.695
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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