Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trhdeThyrotropin releasing hormone degrading enzyme, tandem duplicate 2. (1013 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
  
 0.694
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.634
dld
Dihydrolipoyl dehydrogenase.
  
 0.633
LOC103144083
Thioredoxin reductase 3.
  
 0.577
ENSPFOP00000010087
Thioredoxin reductase 2, tandem duplicate 1.
  
 0.577
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 
 0.537
amt
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
     
 0.520
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 
 0.520
CPQ
Carboxypeptidase Q.
   
 0.510
gclm
Glutamate-cysteine ligase, modifier subunit.
  
 
  0.504
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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