afmid protein (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

afmid

Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (292 aa)

Predicted Functional Partners:

KYNU

0.990

tdo2

0.990

ENSPFOP00000010905

0.987

ENSPFOP00000009802

0.974

LOC103133561

0.974

ENSPFOP00000004711

0.948

LOC103135930

0.939

kyat3

0.939

pfdn1

0.935

pfdn6

0.931

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000004711	ENSPFOP00000010905	ENSPFOP00000004711	ENSPFOP00000010905	Aminoadipate aminotransferase.	Kynurenine 3-monooxygenase.	0.971
ENSPFOP00000004711	KYNU	ENSPFOP00000004711	ENSPFOP00000005220	Aminoadipate aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.970
ENSPFOP00000004711	LOC103135930	ENSPFOP00000004711	ENSPFOP00000007427	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.951
ENSPFOP00000004711	afmid	ENSPFOP00000004711	ENSPFOP00000001617	Aminoadipate aminotransferase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.948
ENSPFOP00000004711	kyat3	ENSPFOP00000004711	ENSPFOP00000017026	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.951
ENSPFOP00000004711	tdo2	ENSPFOP00000004711	ENSPFOP00000019088	Aminoadipate aminotransferase.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.583
ENSPFOP00000009802	ENSPFOP00000010905	ENSPFOP00000009802	ENSPFOP00000010905	Indoleamine 2,3-dioxygenase 1.	Kynurenine 3-monooxygenase.	0.642
ENSPFOP00000009802	KYNU	ENSPFOP00000009802	ENSPFOP00000005220	Indoleamine 2,3-dioxygenase 1.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.972
ENSPFOP00000009802	LOC103133561	ENSPFOP00000009802	ENSPFOP00000017579	Indoleamine 2,3-dioxygenase 1.	Uncharacterized protein.	0.903
ENSPFOP00000009802	LOC103135930	ENSPFOP00000009802	ENSPFOP00000007427	Indoleamine 2,3-dioxygenase 1.	Kynurenine aminotransferase 1.	0.512
ENSPFOP00000009802	afmid	ENSPFOP00000009802	ENSPFOP00000001617	Indoleamine 2,3-dioxygenase 1.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.974
ENSPFOP00000009802	kyat3	ENSPFOP00000009802	ENSPFOP00000017026	Indoleamine 2,3-dioxygenase 1.	Kynurenine aminotransferase 3.	0.512
ENSPFOP00000009802	tdo2	ENSPFOP00000009802	ENSPFOP00000019088	Indoleamine 2,3-dioxygenase 1.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.984
ENSPFOP00000010905	ENSPFOP00000004711	ENSPFOP00000010905	ENSPFOP00000004711	Kynurenine 3-monooxygenase.	Aminoadipate aminotransferase.	0.971
ENSPFOP00000010905	ENSPFOP00000009802	ENSPFOP00000010905	ENSPFOP00000009802	Kynurenine 3-monooxygenase.	Indoleamine 2,3-dioxygenase 1.	0.642
ENSPFOP00000010905	KYNU	ENSPFOP00000010905	ENSPFOP00000005220	Kynurenine 3-monooxygenase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.999
ENSPFOP00000010905	LOC103133561	ENSPFOP00000010905	ENSPFOP00000017579	Kynurenine 3-monooxygenase.	Uncharacterized protein.	0.625
ENSPFOP00000010905	LOC103135930	ENSPFOP00000010905	ENSPFOP00000007427	Kynurenine 3-monooxygenase.	Kynurenine aminotransferase 1.	0.973
ENSPFOP00000010905	afmid	ENSPFOP00000010905	ENSPFOP00000001617	Kynurenine 3-monooxygenase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.987
ENSPFOP00000010905	kyat3	ENSPFOP00000010905	ENSPFOP00000017026	Kynurenine 3-monooxygenase.	Kynurenine aminotransferase 3.	0.973

page 1 of 4

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About