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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001629Si:ch211-130m23.5. (497 aa)    
Predicted Functional Partners:
LOC103154612
Ig_4 domain-containing protein.
   
 0.975
cd3e
Ig_4 domain-containing protein.
   
 0.975
LOC103139595
Ig-like domain-containing protein.
   
 0.908
ENSPFOP00000000523
Spleen tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.
  
 0.812
ENSPFOP00000015505
Tyrosine-protein kinase.
  
 0.812
ENSPFOP00000023628
Spleen tyrosine kinase.
  
 0.812
oxsm
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.736
mcat
Malonyl CoA:ACP acyltransferase (mitochondrial).
  
 0.736
LOC103139924
SH2 domain containing 1A duplicate b.
   
  
 0.721
LOC103131426
Cytochrome b5 reductase 4.
  
 0.720
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.