Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001631SET domain containing 2, histone lysine methyltransferase. (2362 aa)    
Predicted Functional Partners:
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 
 0.969
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.967
supt6h
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
  
 
 0.965
ENSPFOP00000011510
Transcription elongation factor SPT5.
   
 
 0.965
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
    
 
 0.960
supt4h1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 
 0.958
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 0.958
ENSPFOP00000014318
Huntingtin.
   
 
 0.953
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component.
  
 0.951
ENSPFOP00000011898
RTF1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.948
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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