Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001643Cholinergic receptor, nicotinic, alpha 3. (477 aa)    
Predicted Functional Partners:
chrna2
Cholinergic receptor, nicotinic, alpha 2b (neuronal).
    
  0.774
ENSPFOP00000010275
Cholinergic receptor, nicotinic, alpha 4b.
    
  0.774
chrna1
Cholinergic receptor, nicotinic, alpha 1 (muscle).
   
 0.746
LOC103147503
Cholinergic receptor, nicotinic, beta 3b (neuronal).
    
 0.743
LOC103132328
Cholinergic receptor, nicotinic, beta polypeptide 3a.
    
 0.743
ENSPFOP00000020002
Cholinergic receptor, nicotinic, alpha 5.
    
 0.743
LYPD6
LY6/PLAUR domain containing 6.
    
  0.679
ENSPFOP00000009205
Si:ch211-39a7.1.
   
  0.592
LOC103147504
Si:ch73-380n15.2.
   
  0.592
chrna7
Cholinergic receptor, nicotinic, alpha 7 (neuronal).
   
  0.592
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (22%) [HD]