Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tlx1T cell leukemia homeobox 1. (288 aa)    
Predicted Functional Partners:
arx
Aristaless related homeobox a.
    
 
 0.676
rnf151
Ring finger protein 151.
    
 
 0.556
ENSPFOP00000024345
Ring finger protein 41, like.
    
 
 0.542
ENSPFOP00000019489
PR domain containing 13.
    
 
 0.532
znf143
Zinc finger protein 143b.
    
 
 0.531
TBX22
T-box transcription factor 22.
   
 
 0.520
ENSPFOP00000019047
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
  0.501
LOC103154897
Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
      
 0.498
acsl1
Acyl-CoA synthetase long chain family member 1a.
      
 0.468
LOC103148351
5'-nucleotidase, cytosolic II, like 1.
      
 0.467
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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