Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)    
Predicted Functional Partners:
ENSPFOP00000022234
Sphingosine kinase 2.
    
 0.975
SPHK1
Sphingosine kinase 1.
    
 0.968
SPHK1-2
Sphingosine kinase 1.
    
 0.968
LOC103144262
Delta(4)-desaturase, sphingolipid 2.
   
 
 0.955
LOC103154293
Delta(4)-desaturase, sphingolipid 1.
   
 
 0.955
plpp2
Phospholipid phosphatase 2a.
     
 0.952
LOC103142604
Phospholipid phosphatase 2b.
     
 0.952
ENSPFOP00000005125
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.947
ENSPFOP00000003510
Phospholipid phosphatase 1a.
     
 0.938
ENSPFOP00000006409
acidPPc domain-containing protein.
     
 0.938
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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