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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103151004COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)    
Predicted Functional Partners:
cops5
COP9 signalosome subunit 5.
   
 0.999
LOC103131621
COP9 signalosome subunit 8.
   
 0.999
cops2
COP9 signalosome subunit 2.
   
 0.999
cops7a
COP9 constitutive photomorphogenic homolog subunit 7A.
   
 0.999
gps1
G protein pathway suppressor 1.
   
 0.999
cops3
COP9 signalosome subunit 3.
   
 0.999
COPS6
COP9 signalosome subunit 6.
   
 0.989
COPS6-2
COP9 signalosome subunit 6.
   
 0.989
ENSPFOP00000004033
Protein phosphatase 1, regulatory subunit 42.
   
 0.986
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.986
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.