Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pafah1b3Platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit. (223 aa)    
Predicted Functional Partners:
LOC103139247
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.994
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.994
LOC103133987
Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2.
  
  
 
0.955
lpcat2
Lysophosphatidylcholine acyltransferase 2.
     
 0.920
pla2g7
Platelet-activating factor acetylhydrolase.
     
 0.917
LOC103146032
Lysophosphatidylcholine acyltransferase 1.
     
 0.909
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
     
 0.909
lpcat4
Lysophosphatidylcholine acyltransferase 4.
     
  0.900
chpt1
Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
cept1
Choline/ethanolamine phosphotransferase 1b; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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