Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smug1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (278 aa)    
Predicted Functional Partners:
ENSPFOP00000020059
Adenosine deaminase tRNA specific 3.
   
 0.951
ENSPFOP00000015847
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
   0.946
UNG
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 
 0.905
tyms
Thymidylate synthetase.
  
 
 0.880
mbd4
Methyl-CpG binding domain protein 4.
      
 0.860
apex1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 
 0.829
uprt
Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae).
   
 0.803
lmo2
LIM domain only 2 (rhombotin-like 1).
    
   0.801
tk1
Thymidine kinase.
    
 0.767
ENSPFOP00000005659
Nei-like DNA glycosylase 1.
      
 0.756
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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