LOC103146385 protein (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC103146385

Death-domain associated protein. (721 aa)

Predicted Functional Partners:

LOC103133531

0.998

usp7

0.997

mdm2

0.992

sumo1

0.992

atrx

0.991

LOC103133971

0.991

ENSPFOP00000013247

0.990

ENSPFOP00000015853

0.990

tp53

0.987

dnmt1

0.965

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000013247	ENSPFOP00000015853	ENSPFOP00000013247	ENSPFOP00000015853	Si:ch211-1i11.3.	Mitogen-activated protein kinase kinase kinase 5.	0.902
ENSPFOP00000013247	LOC103133531	ENSPFOP00000013247	ENSPFOP00000015832	Si:ch211-1i11.3.	Uncharacterized protein.	0.793
ENSPFOP00000013247	LOC103146385	ENSPFOP00000013247	ENSPFOP00000001724	Si:ch211-1i11.3.	Death-domain associated protein.	0.990
ENSPFOP00000015853	ENSPFOP00000013247	ENSPFOP00000015853	ENSPFOP00000013247	Mitogen-activated protein kinase kinase kinase 5.	Si:ch211-1i11.3.	0.902
ENSPFOP00000015853	LOC103133531	ENSPFOP00000015853	ENSPFOP00000015832	Mitogen-activated protein kinase kinase kinase 5.	Uncharacterized protein.	0.793
ENSPFOP00000015853	LOC103146385	ENSPFOP00000015853	ENSPFOP00000001724	Mitogen-activated protein kinase kinase kinase 5.	Death-domain associated protein.	0.990
LOC103133531	ENSPFOP00000013247	ENSPFOP00000015832	ENSPFOP00000013247	Uncharacterized protein.	Si:ch211-1i11.3.	0.793
LOC103133531	ENSPFOP00000015853	ENSPFOP00000015832	ENSPFOP00000015853	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 5.	0.793
LOC103133531	LOC103146385	ENSPFOP00000015832	ENSPFOP00000001724	Uncharacterized protein.	Death-domain associated protein.	0.998
LOC103133531	mdm2	ENSPFOP00000015832	ENSPFOP00000017399	Uncharacterized protein.	MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.	0.425
LOC103133531	sumo1	ENSPFOP00000015832	ENSPFOP00000017842	Uncharacterized protein.	Small ubiquitin like modifier 1.	0.766
LOC103133531	tp53	ENSPFOP00000015832	ENSPFOP00000007556	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.856
LOC103133971	LOC103146385	ENSPFOP00000019591	ENSPFOP00000001724	Uncharacterized protein.	Death-domain associated protein.	0.991
LOC103133971	atrx	ENSPFOP00000019591	ENSPFOP00000009961	Uncharacterized protein.	Uncharacterized protein.	0.904
LOC103133971	dnmt1	ENSPFOP00000019591	ENSPFOP00000006222	Uncharacterized protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.502
LOC103133971	sumo1	ENSPFOP00000019591	ENSPFOP00000017842	Uncharacterized protein.	Small ubiquitin like modifier 1.	0.508
LOC103133971	tp53	ENSPFOP00000019591	ENSPFOP00000007556	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.902
LOC103146385	ENSPFOP00000013247	ENSPFOP00000001724	ENSPFOP00000013247	Death-domain associated protein.	Si:ch211-1i11.3.	0.990
LOC103146385	ENSPFOP00000015853	ENSPFOP00000001724	ENSPFOP00000015853	Death-domain associated protein.	Mitogen-activated protein kinase kinase kinase 5.	0.990
LOC103146385	LOC103133531	ENSPFOP00000001724	ENSPFOP00000015832	Death-domain associated protein.	Uncharacterized protein.	0.998