| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPFOP00000000639 | ENSPFOP00000008673 | ENSPFOP00000000639 | ENSPFOP00000008673 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | PNP_UDP_1 domain-containing protein. | 0.937 |
| ENSPFOP00000000639 | ENSPFOP00000018078 | ENSPFOP00000000639 | ENSPFOP00000018078 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.960 |
| ENSPFOP00000000639 | LOC103137571 | ENSPFOP00000000639 | ENSPFOP00000012868 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.935 |
| ENSPFOP00000000639 | LOC103142511 | ENSPFOP00000000639 | ENSPFOP00000011434 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.934 |
| ENSPFOP00000000639 | LOC103152273 | ENSPFOP00000000639 | ENSPFOP00000001733 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.964 |
| ENSPFOP00000000639 | TYMP | ENSPFOP00000000639 | ENSPFOP00000012323 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.948 |
| ENSPFOP00000000639 | dpyd | ENSPFOP00000000639 | ENSPFOP00000005844 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.962 |
| ENSPFOP00000000639 | tk1 | ENSPFOP00000000639 | ENSPFOP00000001730 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Thymidine kinase. | 0.958 |
| ENSPFOP00000000639 | uck1 | ENSPFOP00000000639 | ENSPFOP00000006184 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.570 |
| ENSPFOP00000000639 | uprt | ENSPFOP00000000639 | ENSPFOP00000009460 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). | 0.968 |
| ENSPFOP00000008673 | ENSPFOP00000000639 | ENSPFOP00000008673 | ENSPFOP00000000639 | PNP_UDP_1 domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.937 |
| ENSPFOP00000008673 | ENSPFOP00000018078 | ENSPFOP00000008673 | ENSPFOP00000018078 | PNP_UDP_1 domain-containing protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.960 |
| ENSPFOP00000008673 | LOC103137571 | ENSPFOP00000008673 | ENSPFOP00000012868 | PNP_UDP_1 domain-containing protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.936 |
| ENSPFOP00000008673 | LOC103142511 | ENSPFOP00000008673 | ENSPFOP00000011434 | PNP_UDP_1 domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.936 |
| ENSPFOP00000008673 | LOC103152273 | ENSPFOP00000008673 | ENSPFOP00000001733 | PNP_UDP_1 domain-containing protein. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.964 |
| ENSPFOP00000008673 | TYMP | ENSPFOP00000008673 | ENSPFOP00000012323 | PNP_UDP_1 domain-containing protein. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.948 |
| ENSPFOP00000008673 | dpyd | ENSPFOP00000008673 | ENSPFOP00000005844 | PNP_UDP_1 domain-containing protein. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.962 |
| ENSPFOP00000008673 | tk1 | ENSPFOP00000008673 | ENSPFOP00000001730 | PNP_UDP_1 domain-containing protein. | Thymidine kinase. | 0.959 |
| ENSPFOP00000008673 | uck1 | ENSPFOP00000008673 | ENSPFOP00000006184 | PNP_UDP_1 domain-containing protein. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.570 |
| ENSPFOP00000008673 | uprt | ENSPFOP00000008673 | ENSPFOP00000009460 | PNP_UDP_1 domain-containing protein. | Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). | 0.968 |