Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
elp3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (553 aa)    
Predicted Functional Partners:
elp1
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.
   
 0.999
elp2
Elongator acetyltransferase complex subunit 2.
   
 0.998
ENSPFOP00000017040
Elongator acetyltransferase complex subunit 4.
   
 0.991
ENSPFOP00000026412
Elongator acetyltransferase complex subunit 4.
   
 0.991
ENSPFOP00000006777
Elongator acetyltransferase complex subunit 5.
   
 0.990
ENSPFOP00000013417
Elongator acetyltransferase complex subunit 6.
    
 0.990
LOC103150923
Diphthamide biosynthesis 3.
   
 
 0.963
ENSPFOP00000003639
KTI12 chromatin associated homolog.
   
 
 0.958
ENSPFOP00000017529
MMS19 homolog, cytosolic iron-sulfur assembly component.
   
 
 0.931
urm1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically [...]
   
 
 0.927
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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