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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)    
Predicted Functional Partners:
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
0.988
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.984
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.981
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
    
 0.978
ENSPFOP00000008202
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.975
ENSPFOP00000022348
Raf-1 proto-oncogene, serine/threonine kinase a.
   
0.975
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
  
 
0.952
map3k4
Mitogen-activated protein kinase kinase kinase 4.
   
0.941
MOS
MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily.
  
 
0.937
ENSPFOP00000021216
V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily.
  
 
0.937
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.