Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)    
Predicted Functional Partners:
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.991
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.991
ENSPFOP00000008202
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.991
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
0.990
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.990
ENSPFOP00000022348
Raf-1 proto-oncogene, serine/threonine kinase a.
   
0.990
MOS
MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily.
  
 
 
0.936
ksr2
Kinase suppressor of ras 2.
   
 0.923
LOC103133939
Kinase suppressor of ras 1a.
   
 0.923
mapk7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.919
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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