Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSPFOP00000001812Si:ch211-221f10.2. (1204 aa)    
Predicted Functional Partners:
ENSPFOP00000018897
ATP-binding cassette, sub-family C (CFTR/MRP), member 3.
  
  
0.929
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5.
  
  
 
0.901
gopc
Golgi-associated PDZ and coiled-coil motif containing.
    
 0.634
ENSPFOP00000019155
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.631
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.614
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.585
abcg4
ATP-binding cassette, sub-family G (WHITE), member 4a.
   
 0.562
LOC103152983
ATP-binding cassette, sub-family G (WHITE), member 1.
   
 0.562
rnf185
Ring finger protein 185.
    
 0.549
RNF5
Ring finger protein 5.
    
 0.549
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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