Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001831Low density lipoprotein receptor-related protein 5. (1646 aa)    
Predicted Functional Partners:
ENSPFOP00000015559
Dickkopf WNT signaling pathway inhibitor 1a.
    
 0.997
sost
Sclerostin.
    
 0.990
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.988
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.984
dkk2
Dickkopf WNT signaling pathway inhibitor 2.
    
 0.980
LOC103149069
Dickkopf_N domain-containing protein.
    
 0.980
ENSPFOP00000012615
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.978
ENSPFOP00000020094
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.971
ENSPFOP00000020161
Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.971
wnt3
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.970
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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