Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001903P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (392 aa)    
Predicted Functional Partners:
chek2
Checkpoint kinase 2.
   
 0.907
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.881
PANX-2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
     
 0.826
LOC103138228
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
     
 0.826
pkmyt1
Protein kinase, membrane associated tyrosine/threonine 1.
   
 0.796
wee1
Wee1-like protein kinase.
   
 0.796
wee2
Wee1-like protein kinase.
   
 0.796
LOC103155150
Zgc:122979.
    
 
 0.788
dnajb5
J domain-containing protein.
    
 
 0.788
ccne2
Cyclin E2; Belongs to the cyclin family.
   
 0.774
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.