Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001907Homeobox B1a. (343 aa)    
Predicted Functional Partners:
LOC103152427
Pre-B-cell leukemia homeobox 2.
    
 0.888
pknox1
Pbx/knotted 1 homeobox 1.1.
    
 0.853
pbx1
Homeobox domain-containing protein.
    
 0.851
pbx3
Homeobox domain-containing protein.
    
 0.851
pbx4
Pre-B-cell leukemia transcription factor 4.
    
 0.851
LOC103143038
Pre-B-cell leukemia homeobox 1a.
    
 0.851
pknox2
Pbx/knotted 1 homeobox 2.
    
 0.772
egr2
Early growth response 2b.
    
 0.759
ENSPFOP00000003393
Myeloid ecotropic viral integration site 3.
   
 0.746
MAFB
MAF bZIP transcription factor B.
    
 0.743
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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