Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001911Uncharacterized protein. (353 aa)    
Predicted Functional Partners:
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.586
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.585
ENSPFOP00000007356
Intersectin 2a.
    
 0.545
ENSPFOP00000011660
Intersectin 2b.
    
 0.545
itsn1
Intersectin 1 (SH3 domain protein).
    
  0.534
LOC103139106
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.516
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.503
psmd7
Proteasome 26S subunit, non-ATPase 7.
    
  0.489
psmc2
Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.
   
  0.486
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
  0.485
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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