Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
FBXO46F-box protein 46. (661 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
    
 
 0.935
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 
 0.884
CUL3
Cullin 3; Belongs to the cullin family.
    
 
 0.608
ENSPFOP00000010423
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 
 0.608
klhl29
Kelch-like family member 29.
      
 0.564
cacul1
CDK2 associated cullin domain 1; Belongs to the cullin family.
    
 
 0.555
twistnb
Uncharacterized protein.
      
 0.551
thoc7
THO complex 7.
      
 0.550
churc1
Churchill domain containing 1.
      
 0.537
ENSPFOP00000020846
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
      
 0.466
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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