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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001946Rap guanine nucleotide exchange factor (GEF) 5a. (408 aa)    
Predicted Functional Partners:
ENSPFOP00000008817
Uncharacterized protein.
    
 0.896
RIMS2
Regulating synaptic membrane exocytosis 2.
    
 0.896
mras
Muscle RAS oncogene homolog.
    
 0.812
ENSPFOP00000008861
RAS related.
    
 0.731
rras2
RAS related 2.
    
 0.731
ENSPFOP00000001087
Uncharacterized protein.
    
 0.686
rap1a
RAP1A, member of RAS oncogene family b.
    
 0.686
LOC103139095
RAP1A, member of RAS oncogene family a.
    
 0.686
ENSPFOP00000012874
annotation not available
    
 0.686
hras
HRas proto-oncogene, GTPase a.
    
 0.657
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.