Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103135493Glyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)    
Predicted Functional Partners:
ENSPFOP00000010001
Serine--pyruvate aminotransferase.
  
 
 0.984
LOC103130135
Serine--pyruvate aminotransferase.
  
 
 0.984
glyctk
Glycerate kinase.
 
 
 0.974
hoga1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
  
 0.973
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
  
 
 0.944
ENSPFOP00000018160
Hydroxyacid oxidase 2 (long chain).
  
 
 0.944
agxt2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.933
pgp
Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.929
ENSPFOP00000017440
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.925
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.925
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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