Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MARCHF6Membrane associated ring-CH-type finger 6. (915 aa)    
Predicted Functional Partners:
sqle
Squalene epoxidase a.
    
 
 0.943
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.940
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 
 0.902
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.866
amfr
Autocrine motility factor receptor b.
    
 
 0.866
c1qtnf12
C1q and TNF related 12.
    
 
 0.861
ubr2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.800
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.800
ufd1
Ubiquitin recognition factor in ER associated degradation 1.
    
 
 0.775
cnot2
CCR4-NOT transcription complex, subunit 2.
    
 
 0.774
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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