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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vwa2Von Willebrand factor A domain containing 2. (794 aa)    
Predicted Functional Partners:
ENSPFOP00000028219
Uncharacterized protein.
    
  0.674
ENSPFOP00000003242
TROVE domain-containing protein.
    
 0.544
ENSPFOP00000028292
WD_REPEATS_REGION domain-containing protein.
    
  0.543
lig1
DNA ligase.
    
 0.534
ENSPFOP00000016945
Regulatory associated protein of MTOR, complex 1.
    
 0.520
ENSPFOP00000015421
Collagen, type VI, alpha 1.
   
0.514
itgb4
Integrin beta.
    
 0.513
ENSPFOP00000029475
Integrin beta; Belongs to the integrin beta chain family.
    
 0.513
ENSPFOP00000001450
Integrin beta; Belongs to the integrin beta chain family.
    
  0.500
ENSPFOP00000000437
Uncharacterized protein.
   
 
0.499
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.