Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSPFOP00000001971Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (295 aa)    
Predicted Functional Partners:
ENSPFOP00000004410
Ankyrin repeat domain 22.
     
 0.682
LOC103134631
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
   
 
 0.615
LOC103139166
Uncharacterized protein.
   
 
 0.615
psenen
Presenilin enhancer, gamma-secretase subunit.
      
 0.608
ncstn
Nicastrin.
      
 0.591
ENSPFOP00000012537
Nectin cell adhesion molecule 4b.
      
 0.584
ENSPFOP00000004700
Presenilin associated, rhomboid-like a.
      
 0.581
LOC103150886
Rhomboid domain-containing protein.
      
 0.581
rhbdd1
Rhomboid domain containing 1.
      
 0.566
LOC103133088
Si:dkey-31g6.6.
      
 0.566
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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