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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001996Uncharacterized protein. (668 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.865
ENSPFOP00000012340
TIMP metallopeptidase inhibitor 2a.
   
 0.802
ENSPFOP00000022296
TIMP metallopeptidase inhibitor 2b.
   
 0.802
ENSPFOP00000013980
CD44 molecule (Indian blood group) b.
   
 0.726
LOC103139106
Ubiquitin-conjugating enzyme E2 variant 1.
   
 
  0.698
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 2.
    
 0.692
edn1
Endothelin 1.
     
 0.673
vegfa
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
     
 0.664
ENSPFOP00000014993
Kit ligand a.
     
 0.654
ENSPFOP00000005463
Neutrophil cytosolic factor 1.
   
 
 0.640
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.