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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbk1TANK-binding kinase 1. (721 aa)    
Predicted Functional Partners:
sting1
Transmembrane protein 173.
   
 0.995
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.995
ENSPFOP00000002885
Interferon regulatory factor 3.
   
 0.994
optn
Optineurin.
   
 0.994
tank
TRAF family member-associated NFKB activator.
   
 0.994
irf7
Interferon regulatory factor 7.
   
 0.981
sqstm1
Sequestosome 1.
    
 0.981
ENSPFOP00000026086
SKICH domain-containing protein.
    
 0.971
nfkb1
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.
   
 0.969
LOC103140625
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
 0.967
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.