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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
znfx1Zinc finger, NFX1-type containing 1. (1804 aa)    
Predicted Functional Partners:
adar
Adenosine deaminase RNA specific.
   
  
 0.685
tent4a
Terminal nucleotidyltransferase 4A.
    
 
 0.659
tent4b
Terminal nucleotidyltransferase 4B.
    
 
 0.659
LOC103150776
Uncharacterized protein.
    
 
 0.659
LOC103154986
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 
 0.646
LOC103145293
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.646
LOC103139283
Argonaute RISC component 1; Belongs to the argonaute family.
    
 
 0.646
ENSPFOP00000006901
Uncharacterized protein; Belongs to the argonaute family.
    
 
 0.646
dicer1
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
    
 
 0.574
ENSPFOP00000013284
NRDE-2, necessary for RNA interference, domain containing.
      
 0.556
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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