Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
znfx1Zinc finger, NFX1-type containing 1. (1804 aa)    
Predicted Functional Partners:
mavs
CARD_2 domain-containing protein.
     
  0.900
LOC103154986
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 
 0.840
LOC103145293
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.840
LOC103139283
Argonaute RISC component 1; Belongs to the argonaute family.
    
 
 0.840
ENSPFOP00000006901
Uncharacterized protein; Belongs to the argonaute family.
    
 
 0.840
ifih1
Interferon induced with helicase C domain 1.
   
  
 0.805
LOC103144457
Heterogeneous nuclear ribonucleoprotein R.
    
   0.796
syncrip
Synaptotagmin binding, cytoplasmic RNA interacting protein, like.
    
   0.796
ENSPFOP00000031176
Uncharacterized protein.
    
   0.796
tent4a
Terminal nucleotidyltransferase 4A.
    
 
 0.790
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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