STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103155899SCO cytochrome c oxidase assembly protein 1. (303 aa)    
Predicted Functional Partners:
LOC103152227
Cytochrome c oxidase assembly homolog 15 (yeast).
  
 0.956
LOC103147078
Cytochrome c oxidase assembly homolog 11 (yeast).
  
 
 0.863
UQCRFS1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 0.826
LOC103149177
Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1.
    
 0.826
ENSPFOP00000018198
Cytochrome c oxidase copper chaperone COX17.
    
 
 0.775
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.717
LOC103156966
Cytochrome c-1.
    
 0.703
ENSPFOP00000015084
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
  
  
 0.694
ENSPFOP00000012075
Cytochrome c oxidase assembly factor 6.
    
 
 0.688
LOC103155772
NME/NM23 family member 8; Belongs to the NDK family.
  
 
 0.655
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.