Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCTD1Potassium channel tetramerization domain containing 1. (258 aa)    
Predicted Functional Partners:
ENSPFOP00000001593
Transcription factor AP-2 epsilon.
    
 0.780
tfap2b
Transcription factor AP-2 beta.
    
 0.780
tfap2d
Transcription factor AP-2 delta (activating enhancer binding protein 2 delta).
    
 0.780
tfap2c
Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma).
    
 0.780
ENSPFOP00000004987
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.772
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.772
kctd5
Potassium channel tetramerization domain containing 5a.
    
 0.727
kctd2
Potassium channel tetramerization domain containing 2.
    
 
 0.701
yeats4
YEATS domain containing 4.
      
 0.688
coq6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
   
  
 0.577
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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