ENSPFOP00000002183 protein (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSPFOP00000002183

Helicase, POLQ like. (998 aa)

Predicted Functional Partners:

ENSPFOP00000007332

0.985

fancd2

0.961

rad51

0.847

pcna

0.817

fancl

0.787

ENSPFOP00000015303

0.783

ENSPFOP00000002114

0.782

rad51d

0.765

rad50

0.761

pola1

0.759

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000002114	ENSPFOP00000002183	ENSPFOP00000002114	ENSPFOP00000002183	Helicase C-terminal domain-containing protein.	Helicase, POLQ like.	0.782
ENSPFOP00000002114	ENSPFOP00000007332	ENSPFOP00000002114	ENSPFOP00000007332	Helicase C-terminal domain-containing protein.	Polymerase (DNA directed) nu.	0.776
ENSPFOP00000002114	ENSPFOP00000015303	ENSPFOP00000002114	ENSPFOP00000015303	Helicase C-terminal domain-containing protein.	FA complementation group I.	0.998
ENSPFOP00000002114	fancd2	ENSPFOP00000002114	ENSPFOP00000004306	Helicase C-terminal domain-containing protein.	FA complementation group D2.	0.999
ENSPFOP00000002114	fancl	ENSPFOP00000002114	ENSPFOP00000019197	Helicase C-terminal domain-containing protein.	FA complementation group L.	0.999
ENSPFOP00000002114	pcna	ENSPFOP00000002114	ENSPFOP00000010825	Helicase C-terminal domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
ENSPFOP00000002114	pola1	ENSPFOP00000002114	ENSPFOP00000003557	Helicase C-terminal domain-containing protein.	DNA polymerase.	0.914
ENSPFOP00000002114	rad50	ENSPFOP00000002114	ENSPFOP00000003425	Helicase C-terminal domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.850
ENSPFOP00000002114	rad51	ENSPFOP00000002114	ENSPFOP00000014345	Helicase C-terminal domain-containing protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.985
ENSPFOP00000002114	rad51d	ENSPFOP00000002114	ENSPFOP00000001922	Helicase C-terminal domain-containing protein.	RAD51 paralog D.	0.984
ENSPFOP00000002183	ENSPFOP00000002114	ENSPFOP00000002183	ENSPFOP00000002114	Helicase, POLQ like.	Helicase C-terminal domain-containing protein.	0.782
ENSPFOP00000002183	ENSPFOP00000007332	ENSPFOP00000002183	ENSPFOP00000007332	Helicase, POLQ like.	Polymerase (DNA directed) nu.	0.985
ENSPFOP00000002183	ENSPFOP00000015303	ENSPFOP00000002183	ENSPFOP00000015303	Helicase, POLQ like.	FA complementation group I.	0.783
ENSPFOP00000002183	fancd2	ENSPFOP00000002183	ENSPFOP00000004306	Helicase, POLQ like.	FA complementation group D2.	0.961
ENSPFOP00000002183	fancl	ENSPFOP00000002183	ENSPFOP00000019197	Helicase, POLQ like.	FA complementation group L.	0.787
ENSPFOP00000002183	pcna	ENSPFOP00000002183	ENSPFOP00000010825	Helicase, POLQ like.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.817
ENSPFOP00000002183	pola1	ENSPFOP00000002183	ENSPFOP00000003557	Helicase, POLQ like.	DNA polymerase.	0.759
ENSPFOP00000002183	rad50	ENSPFOP00000002183	ENSPFOP00000003425	Helicase, POLQ like.	RAD50 homolog, double strand break repair protein.	0.761
ENSPFOP00000002183	rad51	ENSPFOP00000002183	ENSPFOP00000014345	Helicase, POLQ like.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.847
ENSPFOP00000002183	rad51d	ENSPFOP00000002183	ENSPFOP00000001922	Helicase, POLQ like.	RAD51 paralog D.	0.765