Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hectd3HECT domain containing 3. (856 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
 0.946
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.937
ubb
Ubiquitin B.
    
 0.848
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.839
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.830
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.808
ENSPFOP00000018153
Glutamyl-prolyl-tRNA synthetase.
   
   0.800
mars1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.772
LOC103132215
Ubiquitin-like domain-containing protein.
    
 0.710
ENSPFOP00000004894
Uncharacterized protein.
    
 0.708
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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