Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
USP53Ubiquitin specific peptidase 53. (1049 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.676
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 
 0.647
psmb1
Proteasome subunit beta.
    
   0.581
ENSPFOP00000002357
SEC24 homolog D, COPII coat complex component.
      
 0.578
ubb
Ubiquitin B.
    
  0.558
tcap
Titin-cap (telethonin).
   
 
 0.504
atp8b1
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.499
ENSPFOP00000020493
Zgc:112163.
      
 0.497
ENSPFOP00000001687
VRK serine/threonine kinase 3.
    
   0.491
mphosph6
M-phase phosphoprotein 6.
     
  0.485
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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