Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000003085TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)    
Predicted Functional Partners:
tradd
Tnfrsf1a-associated via death domain.
    
 0.995
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.994
ENSPFOP00000013375
ADP-ribosylation factor 2b.
    
 0.990
LOC103136547
Tumor necrosis factor receptor superfamily, member 1B.
   
 0.990
ENSPFOP00000014923
Mitogen-activated protein kinase kinase kinase 14a.
    
 0.990
LOC103138778
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.987
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.987
ripk2
Receptor-interacting serine-threonine kinase 2.
    
 0.984
birc2
Baculoviral IAP repeat containing 2.
   
 0.984
LOC103139935
X-linked inhibitor of apoptosis.
   
 0.982
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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