Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEL-2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)    
Predicted Functional Partners:
lpl
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
 0.940
LOC103156885
PLAT domain-containing protein.
    
 0.940
LOC103132369
Monoacylglycerol O-acyltransferase 3a.
   
 
 0.920
ENSPFOP00000014558
Monoacylglycerol O-acyltransferase 2.
   
 
 0.920
ENSPFOP00000004740
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
 0.915
lipc
Lipase, hepatic a.
    
  0.906
lipg
Lipase, endothelial.
    
  0.906
mgll
Monoglyceride lipase.
    
 0.903
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
 
0.901
agk
Acylglycerol kinase.
    
  0.901
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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