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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000003364Phosphoinositide phospholipase C. (647 aa)    
Predicted Functional Partners:
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
   
 0.651
ENSPFOP00000002736
PATJ crumbs cell polarity complex component.
   
 0.651
lnx2
Ligand of numb-protein X 2a.
   
 0.651
LOC103140123
Ligand of numb-protein X 2b.
   
 0.651
MPDZ-2
Si:dkey-92j12.5.
   
 0.651
lnx1
Ligand of numb-protein X 1.
   
 0.651
ENSPFOP00000022167
Uncharacterized protein.
   
 0.651
RALB
RAS like proto-oncogene B.
    
  0.630
hras
HRas proto-oncogene, GTPase a.
    
  0.630
LOC103150928
Uncharacterized protein.
    
  0.630
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.