ENSPFOP00000003607 protein (Poecilia formosa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000002611	ENSPFOP00000003607	ENSPFOP00000002611	ENSPFOP00000003607	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Uncharacterized protein.	0.803
ENSPFOP00000002611	tp53	ENSPFOP00000002611	ENSPFOP00000007556	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.992
ENSPFOP00000003607	ENSPFOP00000002611	ENSPFOP00000003607	ENSPFOP00000002611	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.803
ENSPFOP00000003607	ENSPFOP00000017888	ENSPFOP00000003607	ENSPFOP00000017888	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 2.	0.767
ENSPFOP00000003607	LOC103129610	ENSPFOP00000003607	ENSPFOP00000016601	Uncharacterized protein.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	0.690
ENSPFOP00000003607	ash2l	ENSPFOP00000003607	ENSPFOP00000018727	Uncharacterized protein.	Ash2 like, histone lysine methyltransferase complex subunit.	0.682
ENSPFOP00000003607	camkmt	ENSPFOP00000003607	ENSPFOP00000010909	Uncharacterized protein.	Calmodulin-lysine N-methyltransferase.	0.750
ENSPFOP00000003607	helz	ENSPFOP00000003607	ENSPFOP00000013542	Uncharacterized protein.	Helicase with zinc finger.	0.762
ENSPFOP00000003607	plod1	ENSPFOP00000003607	ENSPFOP00000017563	Uncharacterized protein.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.	0.690
ENSPFOP00000003607	plod2	ENSPFOP00000003607	ENSPFOP00000014249	Uncharacterized protein.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2.	0.690
ENSPFOP00000003607	rbbp5	ENSPFOP00000003607	ENSPFOP00000003084	Uncharacterized protein.	Retinoblastoma binding protein 5.	0.680
ENSPFOP00000003607	tp53	ENSPFOP00000003607	ENSPFOP00000007556	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.984
ENSPFOP00000017888	ENSPFOP00000003607	ENSPFOP00000017888	ENSPFOP00000003607	Mitogen-activated protein kinase kinase kinase 2.	Uncharacterized protein.	0.767
ENSPFOP00000017888	tp53	ENSPFOP00000017888	ENSPFOP00000007556	Mitogen-activated protein kinase kinase kinase 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.532
LOC103129610	ENSPFOP00000003607	ENSPFOP00000016601	ENSPFOP00000003607	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	Uncharacterized protein.	0.690
LOC103129610	camkmt	ENSPFOP00000016601	ENSPFOP00000010909	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	Calmodulin-lysine N-methyltransferase.	0.900
LOC103129610	plod1	ENSPFOP00000016601	ENSPFOP00000017563	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.	0.901
LOC103129610	plod2	ENSPFOP00000016601	ENSPFOP00000014249	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2.	0.901
ash2l	ENSPFOP00000003607	ENSPFOP00000018727	ENSPFOP00000003607	Ash2 like, histone lysine methyltransferase complex subunit.	Uncharacterized protein.	0.682
ash2l	rbbp5	ENSPFOP00000018727	ENSPFOP00000003084	Ash2 like, histone lysine methyltransferase complex subunit.	Retinoblastoma binding protein 5.	0.999