| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPFOP00000002501 | ENSPFOP00000012021 | ENSPFOP00000002501 | ENSPFOP00000012021 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.999 |
| ENSPFOP00000002501 | LOC103136077 | ENSPFOP00000002501 | ENSPFOP00000008846 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. | 0.999 |
| ENSPFOP00000002501 | amdhd1 | ENSPFOP00000002501 | ENSPFOP00000001011 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Amidohydrolase domain containing 1. | 0.753 |
| ENSPFOP00000002501 | dmgdh | ENSPFOP00000002501 | ENSPFOP00000007627 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Dimethylglycine dehydrogenase. | 0.972 |
| ENSPFOP00000002501 | ftcd | ENSPFOP00000002501 | ENSPFOP00000004458 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Formimidoyltransferase cyclodeaminase. | 0.978 |
| ENSPFOP00000002501 | mthfd1l | ENSPFOP00000002501 | ENSPFOP00000019722 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. | 0.999 |
| ENSPFOP00000002501 | mthfd2 | ENSPFOP00000002501 | ENSPFOP00000010924 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uncharacterized protein. | 0.999 |
| ENSPFOP00000002501 | mthfs | ENSPFOP00000002501 | ENSPFOP00000019145 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.967 |
| ENSPFOP00000002501 | mtr | ENSPFOP00000002501 | ENSPFOP00000015205 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.946 |
| ENSPFOP00000002501 | shmt2 | ENSPFOP00000002501 | ENSPFOP00000005302 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Serine hydroxymethyltransferase 2 (mitochondrial). | 0.998 |
| ENSPFOP00000012021 | ENSPFOP00000002501 | ENSPFOP00000012021 | ENSPFOP00000002501 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ENSPFOP00000012021 | LOC103136077 | ENSPFOP00000012021 | ENSPFOP00000008846 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. | 0.989 |
| ENSPFOP00000012021 | dmgdh | ENSPFOP00000012021 | ENSPFOP00000007627 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Dimethylglycine dehydrogenase. | 0.984 |
| ENSPFOP00000012021 | ftcd | ENSPFOP00000012021 | ENSPFOP00000004458 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Formimidoyltransferase cyclodeaminase. | 0.981 |
| ENSPFOP00000012021 | mthfd1l | ENSPFOP00000012021 | ENSPFOP00000019722 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. | 0.989 |
| ENSPFOP00000012021 | mthfd2 | ENSPFOP00000012021 | ENSPFOP00000010924 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Uncharacterized protein. | 0.901 |
| ENSPFOP00000012021 | mthfs | ENSPFOP00000012021 | ENSPFOP00000019145 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.984 |
| ENSPFOP00000012021 | mtr | ENSPFOP00000012021 | ENSPFOP00000015205 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.698 |
| ENSPFOP00000012021 | shmt2 | ENSPFOP00000012021 | ENSPFOP00000005302 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | Serine hydroxymethyltransferase 2 (mitochondrial). | 0.989 |
| LOC103136077 | ENSPFOP00000002501 | ENSPFOP00000008846 | ENSPFOP00000002501 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
