smyd5 protein (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000013189	smyd5	ENSPFOP00000013189	ENSPFOP00000004587	NOP2 nucleolar protein homolog (yeast); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	SMYD family member 5.	0.675
ENSPFOP00000013714	ENSPFOP00000016384	ENSPFOP00000013714	ENSPFOP00000016384	SET domain containing 1A, histone lysine methyltransferase.	Lysine (K)-specific methyltransferase 2E.	0.519
ENSPFOP00000013714	ENSPFOP00000016997	ENSPFOP00000013714	ENSPFOP00000016997	SET domain containing 1A, histone lysine methyltransferase.	RRM domain-containing protein.	0.544
ENSPFOP00000013714	SMYD3	ENSPFOP00000013714	ENSPFOP00000010761	SET domain containing 1A, histone lysine methyltransferase.	SET and MYND domain containing 3.	0.703
ENSPFOP00000013714	setd1b	ENSPFOP00000013714	ENSPFOP00000019894	SET domain containing 1A, histone lysine methyltransferase.	SET domain containing 1B, histone lysine methyltransferase a.	0.562
ENSPFOP00000013714	setd3	ENSPFOP00000013714	ENSPFOP00000007125	SET domain containing 1A, histone lysine methyltransferase.	Protein-histidine N-methyltransferase.	0.654
ENSPFOP00000013714	smyd4	ENSPFOP00000013714	ENSPFOP00000012373	SET domain containing 1A, histone lysine methyltransferase.	SET and MYND domain containing 4.	0.565
ENSPFOP00000013714	smyd5	ENSPFOP00000013714	ENSPFOP00000004587	SET domain containing 1A, histone lysine methyltransferase.	SMYD family member 5.	0.667
ENSPFOP00000016384	ENSPFOP00000013714	ENSPFOP00000016384	ENSPFOP00000013714	Lysine (K)-specific methyltransferase 2E.	SET domain containing 1A, histone lysine methyltransferase.	0.519
ENSPFOP00000016384	ENSPFOP00000016997	ENSPFOP00000016384	ENSPFOP00000016997	Lysine (K)-specific methyltransferase 2E.	RRM domain-containing protein.	0.519
ENSPFOP00000016384	SMYD3	ENSPFOP00000016384	ENSPFOP00000010761	Lysine (K)-specific methyltransferase 2E.	SET and MYND domain containing 3.	0.529
ENSPFOP00000016384	setd1b	ENSPFOP00000016384	ENSPFOP00000019894	Lysine (K)-specific methyltransferase 2E.	SET domain containing 1B, histone lysine methyltransferase a.	0.519
ENSPFOP00000016384	setd3	ENSPFOP00000016384	ENSPFOP00000007125	Lysine (K)-specific methyltransferase 2E.	Protein-histidine N-methyltransferase.	0.409
ENSPFOP00000016384	smyd5	ENSPFOP00000016384	ENSPFOP00000004587	Lysine (K)-specific methyltransferase 2E.	SMYD family member 5.	0.687
ENSPFOP00000016384	tp53	ENSPFOP00000016384	ENSPFOP00000007556	Lysine (K)-specific methyltransferase 2E.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.609
ENSPFOP00000016997	ENSPFOP00000013714	ENSPFOP00000016997	ENSPFOP00000013714	RRM domain-containing protein.	SET domain containing 1A, histone lysine methyltransferase.	0.544
ENSPFOP00000016997	ENSPFOP00000016384	ENSPFOP00000016997	ENSPFOP00000016384	RRM domain-containing protein.	Lysine (K)-specific methyltransferase 2E.	0.519
ENSPFOP00000016997	SMYD3	ENSPFOP00000016997	ENSPFOP00000010761	RRM domain-containing protein.	SET and MYND domain containing 3.	0.656
ENSPFOP00000016997	setd1b	ENSPFOP00000016997	ENSPFOP00000019894	RRM domain-containing protein.	SET domain containing 1B, histone lysine methyltransferase a.	0.540
ENSPFOP00000016997	setd3	ENSPFOP00000016997	ENSPFOP00000007125	RRM domain-containing protein.	Protein-histidine N-methyltransferase.	0.591