Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
plekha8Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8. (563 aa)    
Predicted Functional Partners:
mnat1
MNAT1 component of CDK activating kinase.
      
 0.693
tmtc4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.680
trip4
Thyroid hormone receptor interactor 4.
      
 0.680
rspry1
Ring finger and SPRY domain containing 1.
      
 0.653
gpatch3
G patch domain containing 3.
      
 0.650
ENSPFOP00000006633
Uncharacterized protein.
      
 0.641
eaf1
ELL associated factor 1.
      
 0.632
snx20
Sorting nexin 20.
      
 0.583
cope
Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.
   
    0.583
ENSPFOP00000025666
ADP-ribosylation factor-like 2 binding protein.
      
 0.560
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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