Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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bloc1s6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (169 aa)    
Predicted Functional Partners:
bloc1s3
Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.
    
 0.999
dtnbp1
Dystrobrevin binding protein 1b.
    
 0.999
bloc1s1
Biogenesis of lysosomal organelles complex-1, subunit 1.
    
 0.999
LOC103135163
Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.
   
 0.997
snapin
SNAP associated protein.
    
 0.995
bloc1s5
Biogenesis of lysosomal organelles complex-1, subunit 5, muted.
    
 0.995
bloc1s2
Biogenesis of lysosomal organelles complex-1, subunit 2.
    
 0.994
ENSPFOP00000009072
Uncharacterized protein.
   
    0.962
ENSPFOP00000007290
Uncharacterized protein.
    
 0.930
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
     
 0.870
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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