STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103139283Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)    
Predicted Functional Partners:
dicer1
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
   
 0.954
drosha
Uncharacterized protein.
   
 0.876
tarbp2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.866
prkra
Protein kinase, interferon-inducible double stranded RNA dependent activator.
    
 0.866
ENSPFOP00000009029
Trinucleotide repeat containing adaptor 6A.
    
 0.864
ENSPFOP00000011791
Trinucleotide repeat containing adaptor 6C2.
    
 0.864
LOC103141734
Trinucleotide repeat containing adaptor 6C1.
    
 0.864
mff
Mitochondrial fission factor.
   
 0.840
mrpl44
Mitochondrial ribosomal protein L44.
   
 0.840
stau2
Staufen double-stranded RNA binding protein 2.
    
 0.825
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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