STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
e2f4E2F transcription factor 4. (387 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma 1.
   
 0.992
tfdp1
Transcription factor.
   
 0.991
LOC103148634
Retinoblastoma-like 2 (p130).
   
 0.983
ENSPFOP00000019273
Retinoblastoma-like 1 (p107).
   
 0.981
ENSPFOP00000027857
RB_B domain-containing protein.
   
 0.981
LOC103149412
Mothers against decapentaplegic homolog.
    
 0.922
SMAD3
Mothers against decapentaplegic homolog.
    
 0.921
smad3
Mothers against decapentaplegic homolog.
    
 0.920
ENSPFOP00000019994
Mothers against decapentaplegic homolog.
    
 0.919
LOC103152383
Mothers against decapentaplegic homolog.
    
 0.914
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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