STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000006959N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (428 aa)    
Predicted Functional Partners:
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 0.956
galc
Galactosylceramidase b.
     
 0.953
ENSPFOP00000022523
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.953
gba2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.949
acer2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.947
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.943
ENSPFOP00000001619
UDP-glucose ceramide glucosyltransferase.
     
 0.939
ENSPFOP00000006789
Neutral ceramidase.
     
 0.935
LOC103133054
Neutral ceramidase-like.
     
 0.935
ENSPFOP00000005125
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.934
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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