STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcph1Microcephalin 1. (808 aa)    
Predicted Functional Partners:
slf1
SMC5-SMC6 complex localization factor 1.
   
 0.950
brca2
BRCA2 DNA repair associated.
   
 0.922
nbn
Nibrin.
    
 0.916
ENSPFOP00000003275
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.914
ENSPFOP00000006168
ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.900
babam1
BRISC and BRCA1 A complex member 1.
    
 0.898
ENSPFOP00000013687
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.896
topbp1
DNA topoisomerase II binding protein 1.
   
 0.894
terf2
HTH myb-type domain-containing protein.
    
  0.884
chek2
Checkpoint kinase 2.
   
 0.868
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.