ENSPFOP00000008685 protein (Poecilia formosa)

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Score

ENSPFOP00000008685

Nucleoside diphosphate kinase. (189 aa)

Predicted Functional Partners:

ak3

0.972

nme6

0.966

cmpk2

0.966

ENSPFOP00000018717

0.966

ENSPFOP00000020012

0.964

hddc3

0.963

CMPK1

0.961

dut

0.960

guk1

0.959

nme7

0.958

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMPK1	ENSPFOP00000008685	ENSPFOP00000016683	ENSPFOP00000008685	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.961
CMPK1	ENSPFOP00000018717	ENSPFOP00000016683	ENSPFOP00000018717	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxythymidylate kinase (thymidylate kinase).	0.844
CMPK1	ENSPFOP00000020012	ENSPFOP00000016683	ENSPFOP00000020012	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.951
CMPK1	ak3	ENSPFOP00000016683	ENSPFOP00000019809	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.773
CMPK1	cmpk2	ENSPFOP00000016683	ENSPFOP00000012026	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.976
CMPK1	dut	ENSPFOP00000016683	ENSPFOP00000029503	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxyuridine triphosphatase.	0.956
CMPK1	guk1	ENSPFOP00000016683	ENSPFOP00000012699	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Guanylate kinase 1a.	0.710
CMPK1	hddc3	ENSPFOP00000016683	ENSPFOP00000011148	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HD domain containing 3.	0.692
CMPK1	nme6	ENSPFOP00000016683	ENSPFOP00000009087	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.946
CMPK1	nme7	ENSPFOP00000016683	ENSPFOP00000000477	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.948
ENSPFOP00000008685	CMPK1	ENSPFOP00000008685	ENSPFOP00000016683	Nucleoside diphosphate kinase.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.961
ENSPFOP00000008685	ENSPFOP00000018717	ENSPFOP00000008685	ENSPFOP00000018717	Nucleoside diphosphate kinase.	Deoxythymidylate kinase (thymidylate kinase).	0.966
ENSPFOP00000008685	ENSPFOP00000020012	ENSPFOP00000008685	ENSPFOP00000020012	Nucleoside diphosphate kinase.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.964
ENSPFOP00000008685	ak3	ENSPFOP00000008685	ENSPFOP00000019809	Nucleoside diphosphate kinase.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.972
ENSPFOP00000008685	cmpk2	ENSPFOP00000008685	ENSPFOP00000012026	Nucleoside diphosphate kinase.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.966
ENSPFOP00000008685	dut	ENSPFOP00000008685	ENSPFOP00000029503	Nucleoside diphosphate kinase.	Deoxyuridine triphosphatase.	0.960
ENSPFOP00000008685	guk1	ENSPFOP00000008685	ENSPFOP00000012699	Nucleoside diphosphate kinase.	Guanylate kinase 1a.	0.959
ENSPFOP00000008685	hddc3	ENSPFOP00000008685	ENSPFOP00000011148	Nucleoside diphosphate kinase.	HD domain containing 3.	0.963
ENSPFOP00000008685	nme6	ENSPFOP00000008685	ENSPFOP00000009087	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.966
ENSPFOP00000008685	nme7	ENSPFOP00000008685	ENSPFOP00000000477	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.958