STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)    
Predicted Functional Partners:
LOC103147315
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 0.962
LOC103135363
Uncharacterized protein.
    
 0.955
LOC103155140
G protein subunit alpha q.
    
 0.950
LOC103146574
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.945
LOC103142608
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.942
itpr1
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 0.940
ENSPFOP00000016031
Inositol 1,4,5-trisphosphate receptor, type 2.
   
 0.940
LOC103155141
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.939
GNA14
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.938
LOC103135359
Guanine nucleotide-binding protein subunit alpha-14-like.
    
 0.938
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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