STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000015725Annexin. (332 aa)    
Predicted Functional Partners:
ENSPFOP00000009357
Protein S100; Belongs to the S-100 family.
   
 0.973
ENSPFOP00000010696
PDZ domain-containing protein.
   
 0.747
ENSPFOP00000024434
Uncharacterized protein.
   
 0.747
LOC103144480
EF-hand domain-containing protein.
   
 0.745
LOC103144493
Protein S100; Belongs to the S-100 family.
   
 0.745
ENSPFOP00000014874
Uncharacterized protein; Belongs to the S-100 family.
   
 0.745
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.743
LOC103138298
Periaxin.
   
 0.739
ENSPFOP00000019626
PDZ domain-containing protein.
   
 0.739
ENSPFOP00000022448
Uncharacterized protein.
   
 0.739
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.